Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
EFL21236.1PE-PGRS family protein. (1067 aa)    
Predicted Functional Partners:
EFL22809.1
Sensor histidine kinase/response regulator.
   
 0.919
EFL23898.1
Putative tetratricopeptide repeat protein.
  
 0.911
EFL27138.1
Sensor histidine kinase/response regulator.
   
 0.827
EFL23831.1
Conserved hypothetical protein.
 
 
 0.722
EFL25721.1
Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
  0.711
htpG
Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.
  
 0.711
EFL21234.1
Putative polysaccharide biosynthesis protein.
       0.709
EFL27700.1
DnaJ domain protein.
  
 
 0.705
EFL23393.1
Putative ATP-dependent DNA helicase PcrA.
   
  0.704
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.695
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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