STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmFB12 binding domain/ArgK/methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1083 aa)    
Predicted Functional Partners:
EFL20710.1
methylmalonyl-CoA mutase, alpha subunit.
 
0.999
EFL20712.1
methylmalonyl-CoA mutase, beta subunit.
 
 0.999
EFL22347.1
methylmalonyl-CoA mutase.
 
0.999
EFL24122.1
Ferredoxin oxidoreductase, alpha subunit.
  
 
 0.978
EFL23201.1
Putative B12 binding domain protein.
  
 0.947
EFL20795.1
Modular polyketide synthase.
   
 0.934
EFL20798.1
Modular polyketide synthase; Unextendable partial coding region.
   
 0.934
EFL20814.1
Modular polyketide synthase.
   
 0.934
EFL23200.1
Methylaspartate mutase subunit E (MutE) superfamily protein.
   
 0.934
EFL23224.1
Modular polyketide synthase; Unextendable partial coding region.
   
 0.934
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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