Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL21300.1Pyridoxal-5-phosphate-dependent enzyme, beta subunit. (363 aa)    
Predicted Functional Partners:
EFL21302.1
Major facilitator superfamily transporter MFS_1.
 
  
 0.986
EFL21299.1
Conserved hypothetical protein.
 
     0.902
EFL24725.1
Cys/Met metabolism PLP-dependent enzyme family protein.
 
 0.899
EFL21304.1
Putative transporter substrate-binding protein.
 
    0.880
EFL23614.1
Cystathionine gamma-synthase.
 
 0.880
EFL21303.1
Methyltransferase domain protein.
 
     0.842
EFL21301.1
Mandelate racemase/muconate lactonizing enzyme family protein.
 
     0.820
EFL21305.1
Peptide/nickel/opine uptake family ABC transporter, permease.
 
     0.817
EFL24557.1
Putative assimilatory nitrate reductase/sulfite reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 
 0.786
EFL27376.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.782
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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