Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL21313.1Hydroxypyruvate isomerase; Belongs to the hyi family. (277 aa)    
Predicted Functional Partners:
EFL21314.1
2-hydroxy-3-oxopropionate reductase.
 
 0.995
EFL21315.1
Glyoxylate carboligase; Belongs to the TPP enzyme family.
 
 
 0.989
EFL26913.1
2 superfamily AP endonuclease; Belongs to the hyi family.
  
  
 
0.887
EFL20389.1
D-isomer specific 2-hydroxyacid dehydrogenase.
   
 
 0.864
EFL26416.1
Putative 3-hydroxybutyrate dehydrogenase.
 
 0.837
EFL22202.1
Putative isomerase.
 
  
  0.727
EFL27968.1
6-phosphogluconate dehydrogenase, NAD-binding.
 
 
 0.727
EFL22459.1
Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
     0.721
EFL22460.1
Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
     0.672
EFL22461.1
OHCU decarboxylase.
 
     0.659
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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