STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL21313.1Hydroxypyruvate isomerase; Belongs to the hyi family. (277 aa)    
Predicted Functional Partners:
EFL21314.1
2-hydroxy-3-oxopropionate reductase.
 
 0.996
EFL21315.1
Glyoxylate carboligase; Belongs to the TPP enzyme family.
 
 
 0.992
EFL26913.1
2 superfamily AP endonuclease; Belongs to the hyi family.
  
  
 
0.913
EFL20389.1
D-isomer specific 2-hydroxyacid dehydrogenase.
   
 
 0.884
EFL26416.1
Putative 3-hydroxybutyrate dehydrogenase.
 
 0.874
EFL22202.1
Putative isomerase.
 
  
  0.785
EFL27968.1
6-phosphogluconate dehydrogenase, NAD-binding.
 
 
 0.748
EFL28596.1
D-isomer specific 2-hydroxyacid dehydrogenase.
    
  0.748
EFL22459.1
Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
     0.742
EFL22460.1
Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
     0.697
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.