Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL21315.1Glyoxylate carboligase; Belongs to the TPP enzyme family. (592 aa)    
Predicted Functional Partners:
EFL21314.1
2-hydroxy-3-oxopropionate reductase.
 
 
 0.994
EFL21313.1
Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 
 0.989
EFL26913.1
2 superfamily AP endonuclease; Belongs to the hyi family.
  
 
 0.904
EFL22456.1
Malate synthase A; Belongs to the malate synthase family.
    
 0.897
EFL20389.1
D-isomer specific 2-hydroxyacid dehydrogenase.
 
  
 0.887
EFL22348.1
Citrate (Pro-3S)-lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
   
 
  0.856
EFL22433.1
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.
     
  0.855
EFL23292.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
     
  0.855
EFL25713.1
Oxidoreductase, FAD-binding.
     
  0.855
EFL26605.1
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Unextendable partial coding region.
     
  0.855
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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