STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL21374.1CBS domain pair protein; Truncated CDS. (438 aa)    
Predicted Functional Partners:
EFL22401.1
Gamma-glutamyltransferase.
 
  
 0.650
EFL25630.1
Putative glutamate dehydrogenase, NAD-specific.
  
  
  0.626
EFL21372.1
Putative CAAX amino protease family protein.
       0.605
glsA
Thermolabile glutaminase; Belongs to the glutaminase family.
   
 
  0.592
egtA
Glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
    
  0.588
nuoI
NADH-quinone oxidoreductase subunit I 2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
  0.578
EFL23651.1
Putative gamma-glutamyltranspeptidase.
    
 0.575
EFL25599.1
Putative cupin domain protein.
  
  
  0.570
EFL23614.1
Cystathionine gamma-synthase.
     
 0.519
EFL24725.1
Cys/Met metabolism PLP-dependent enzyme family protein.
     
 0.519
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.