Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL21386.1Putative membrane associated protein. (312 aa)    
Predicted Functional Partners:
EFL21384.1
Putative membrane protein.
 
   
 0.901
EFL21385.1
Mannose-1-phosphate guanyltransferase.
       0.769
EFL21381.1
Conserved hypothetical protein.
     
 0.687
EFL21387.1
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyl-transferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
   
 0.628
disA
Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
     0.601
EFL26870.1
Putative DNA-binding protein.
 
    0.601
EFL24852.1
Conserved hypothetical protein.
  
     0.596
EFL21382.1
MerR family transcriptional regulator; Truncated CDS; unextendable partial coding region.
       0.572
EFL21383.1
Forkhead-associated.
       0.572
EFL21380.1
MerR family transcriptional regulator.
       0.508
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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