Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL21399.1acetoacetate-CoA ligase. (663 aa)    
Predicted Functional Partners:
EFL22081.1
Fatty oxidation complex, alpha subunit.
  
 0.882
EFL25925.1
hydroxymethylglutaryl-CoA lyase (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase).
 
 
 0.881
EFL21454.1
Nonspecific lipid-transfer protein.
   
 
  0.867
EFL23165.1
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
  0.867
EFL25529.1
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
  0.867
EFL26549.1
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
  0.867
EFL22342.1
3-hydroxybutyryl-CoA dehydrogenase.
   
 
 0.865
EFL23180.1
Putative 3-hydroxyacyl-CoA dehydrogenase.
   
 
 0.865
EFL23230.1
3-hydroxybutyryl-CoA dehydrogenase.
   
 
 0.865
EFL24631.1
3-hydroxyacyl-CoA dehydrogenase PaaC.
   
 
 0.865
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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