STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL21591.1Ring-cleaving dioxygenase. (134 aa)    
Predicted Functional Partners:
EFL22347.1
methylmalonyl-CoA mutase.
    
 0.795
EFL24122.1
Ferredoxin oxidoreductase, alpha subunit.
     
 0.706
icmF
B12 binding domain/ArgK/methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.685
EFL20777.1
Polyketide synthase.
  
 0.648
EFL28210.1
Erythronolide synthase, modules 5 and 6 (ORF 3) (6-deoxyerythronolide B synthase III) (DEBS 3).
  
 0.648
EFL29029.1
Benzoate dioxygenase, ferredoxin reductase component.
  
 
 0.620
EFL20710.1
methylmalonyl-CoA mutase, alpha subunit.
    
 0.609
EFL20712.1
methylmalonyl-CoA mutase, beta subunit.
    
 0.609
EFL24888.1
TetR family transcriptional regulator.
       0.605
EFL21592.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.573
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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