Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL21757.1Conserved hypothetical protein. (210 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.887
EFL24562.1
Putative membrane protein.
    
 0.833
EFL21756.1
Putative membrane protein.
       0.749
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.744
EFL26817.1
Anthranilate synthase, phenazine specific.
  
  
  0.695
EFL27360.1
Phosphatidylinositol 3- and 4-kinase.
    
  0.693
EFL22263.1
Anthranilate synthase, phenazine specific.
  
  
  0.692
EFL28954.1
SNF2/helicase domain protein.
  
 0.680
EFL23473.1
Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.672
EFL26999.1
Glyceraldehyde-3-phosphate dehydrogenase, type I; Unextendable partial coding region; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.672
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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