Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL21786.1Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family. (739 aa)    
Predicted Functional Partners:
EFL24122.1
Ferredoxin oxidoreductase, alpha subunit.
  
 
 0.992
EFL23292.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
   
 
 0.955
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.953
EFL26930.1
Glutamate synthase large subunit.
     
 0.941
EFL28377.1
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 
 0.931
EFL29270.1
4Fe-4S ferredoxin, iron-sulfur binding.
  
 
 0.931
EFL24123.1
Putative oxidoreductase.
  
 
 0.928
EFL22633.1
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.910
EFL28277.1
Aconitate hydratase 1.
  
 
 0.910
EFL28253.1
Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.895
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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