Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL21805.1Helix-turn-helix domain-containing protein. (104 aa)    
Predicted Functional Partners:
EFL24730.1
Putative regulator.
  
   
 0.826
EFL21855.1
Sporulation and cell division protein SsgA.
  
   
 0.783
pyrR
PyrR bifunctional protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.771
EFL22906.1
RNA polymerase sigma factor WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.763
EFL22091.1
Sporulation and cell division protein SsgA.
  
   
 0.760
EFL22845.1
Putative BldB protein.
  
   
 0.759
whiA
Probable transcriptional regulatory protein whia; Involved in cell division and chromosome segregation.
      
 0.663
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
       0.658
EFL24990.1
Putative thymidylate kinase.
  
 
  0.652
EFL21796.1
mIHF.
       0.634
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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