Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
EFL21916.1uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (413 aa)    
Predicted Functional Partners:
EFL24220.1
uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase.
 
 
0.998
hemC-2
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.997
EFL22511.1
Putative secreted protein.
 
 0.996
EFL20702.1
precorrin-3B C(17)-methyltransferase; Truncated CDS; unextendable partial coding region.
 
 
 0.995
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.995
EFL27119.1
Cobalamin (vitamin B12) biosynthesis CbiX protein; Truncated CDS; unextendable partial coding region.
 
 0.995
EFL27120.1
CbiG protein/precorrin-3B C17-methyltransferase.
 
 
 0.994
EFL25669.1
uroporphyrinogen-III synthase domain protein.
 
 
 0.987
EFL24219.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.986
EFL21918.1
Putative methyltransferase.
 
 
 0.979
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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