Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL21923.1Phosphatase YfbT. (223 aa)    
Predicted Functional Partners:
EFL26518.1
Phosphatase YfbT.
  
  
 
0.880
EFL21021.1
Putative hydrolase.
  
  
  0.803
EFL21924.1
Putative integral membrane protein; Overlaps another CDS with the same product name.
       0.789
EFL21925.1
Putative integral membrane protein; Overlaps another CDS with the same product name.
       0.789
guaA
GMP synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
 
 
 0.764
EFL21921.1
ABC transporter, permease.
 
     0.763
EFL21919.1
Putative acetyltransferase.
       0.661
EFL28508.1
D-mannonate oxidoreductase (Fructuronate reductase); Belongs to the mannitol dehydrogenase family.
    
  0.638
EFL28847.1
D-mannonate oxidoreductase (Fructuronate reductase); Belongs to the mannitol dehydrogenase family.
    
  0.638
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.601
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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