Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL21964.1Putative helix-turn-helix domain protein. (90 aa)    
Predicted Functional Partners:
EFL26112.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 0.875
EFL22809.1
Sensor histidine kinase/response regulator.
   
 0.832
EFL27601.1
Polyketide synthase; Truncated CDS.
  
 
 0.782
EFL21630.1
Non-ribosomal peptide synthetase.
  
 0.777
EFL21634.1
Non-ribosomal peptide synthetase/polyketide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.776
EFL25531.1
Cystathionine beta-synthase.
  
 
 0.757
EFL22321.1
Catalase HPII.
  
 
 0.752
EFL21629.1
Pyoverdine chromophore synthetase.
  
 
 0.751
EFL27376.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
  0.744
sigA
RNA polymerase sigma (70) factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.739
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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