STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL22050.11-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein. (248 aa)    
Predicted Functional Partners:
EFL22049.1
Hopanoid biosynthesis associated radical SAM protein HpnH.
 
   
 0.980
EFL22051.1
Squalene-hopene cyclase.
 
   
 0.976
EFL22053.1
Putative squalene/phytoene dehydrogenase.
 
   
 0.956
EFL22052.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.936
EFL22047.1
Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
   
 0.919
EFL22048.1
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
       0.731
EFL22046.1
LigA protein; Belongs to the serpin family.
       0.709
EFL22054.1
Squalene synthase HpnD.
 
   
 0.657
EFL23032.1
Putative glycine-sarcosine methyltransferase.
  
 
 0.638
EFL22055.1
Squalene synthase HpnC.
 
   
 0.634
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.