Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL22239.1Putative pterin-4-alpha-carbinolamine dehydratase (PHS)(4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolaminedehydratase) (PCD). (102 aa)    
Predicted Functional Partners:
EFL22240.1
Xre family toxin-antitoxin system, antitoxin component.
       0.796
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.619
EFL26971.1
Putative ADP-ribosylglycohydrolase.
       0.572
EFL28327.1
Putative 4-hydroxyphenylpyruvate dioxygenase; Truncated CDS; unextendable partial coding region.
 
  
 0.559
EFL25708.1
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.555
EFL22235.1
Conserved hypothetical protein.
       0.535
EFL22236.1
Cyclopropane-fatty-acyl-phospholipid synthase; Truncated CDS.
       0.535
EFL22237.1
Cyclopropane-fatty-acyl-phospholipid synthase.
       0.535
EFL22238.1
Amine oxidase, flavin-containing; Truncated CDS.
       0.535
EFL22231.1
Probable methyltransferase.
       0.514
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (18%) [HD]