STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL22259.1Conserved hypothetical protein. (176 aa)    
Predicted Functional Partners:
EFL22258.1
Putative long-chain acyl-CoA synthetase.
 
   
 0.909
EFL22261.1
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase.
 
 
  0.804
EFL22260.1
Isochorismatase.
 
     0.799
EFL22257.1
Non-ribosomal peptide synthetase.
 
    0.769
EFL22263.1
Anthranilate synthase, phenazine specific.
 
     0.760
EFL22256.1
Acyl-[acyl-carrier-protein] dehydrogenase MbtN (Acyl-ACPdehydrogenase mbtN) (Mycobactin synthetase protein N).
 
 
   0.743
EFL22248.1
Methyltransferase domain protein.
 
 
   0.665
EFL22254.1
Putative LigA.
  
     0.658
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.619
EFL22247.1
Putative long-chain acyl-CoA synthetase.
 
   
 0.595
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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