Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL22314.1Probable transcriptional regulator. (247 aa)    
Predicted Functional Partners:
EFL22315.1
PAS domain protein.
 
  
  0.846
EFL22313.1
Conserved hypothetical protein.
       0.784
EFL24220.1
uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase.
  
 
 0.696
EFL22311.1
Putative metallo-beta-lactamase domain protein.
       0.656
EFL20573.1
Putative mucin-2 (MUC-2) (Intestinal mucin-2).
  
 
 0.627
EFL25251.1
Conserved hypothetical protein.
  
 
 0.627
EFL25299.1
Putative amino acid binding protein.
  
 
 0.627
EFL26717.1
Conserved hypothetical protein.
  
 
 0.627
EFL26954.1
Putative branched chain amino acid binding protein.
  
 
 0.627
EFL22809.1
Sensor histidine kinase/response regulator.
   
 
 0.625
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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