STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL22317.1F420-dependent glucose-6-phosphate dehydrogenase FGD1. (321 aa)    
Predicted Functional Partners:
fbiA
LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.744
EFL22682.1
Probable alkanesulfonate monooxygenase.
  
     0.690
EFL26583.1
N5,N10-methylenetetrahydromethanopterin reductase-related protein.
  
     0.689
EFL28555.1
Conserved hypothetical protein.
  
  
 0.682
fbiB
Gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0.
 
  
 0.670
EFL21630.1
Non-ribosomal peptide synthetase.
   
 0.667
EFL22318.1
Pyruvate dehydrogenase (cytochrome); Belongs to the TPP enzyme family.
       0.625
EFL27172.1
Conserved hypothetical protein.
  
  
 0.617
EFL28917.1
Putative oxidoreductase.
  
     0.615
EFL21120.1
Probable F420-dependent oxidoreductase, MSMEG_2516 family.
  
     0.611
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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