STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Coexpression
Experiments
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[Homology]
Score
EFL22363.1methylated-DNA-protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (167 aa)    
Predicted Functional Partners:
EFL22364.1
Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Unextendable partial coding region.
  
 
 0.757
EFL23444.1
DNA-3-methyladenine glycosylase I.
   
 0.697
EFL27967.1
Putative AraC family transcriptional regulator.
  
 
 0.615
EFL28684.1
DNA-3-methyladenine glycosylase II.
  
 
 0.615
EFL22361.1
LigA protein.
       0.606
EFL22362.1
RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily.
       0.606
EFL23591.1
Histone macro-H2A1-related protein.
  
    0.579
EFL22375.1
P49 protein.
       0.572
EFL23903.1
ArsR family transcriptional regulator.
       0.572
EFL23904.1
Cadmium-exporting ATPase.
       0.572
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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