Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL22433.12-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase. (217 aa)    
Predicted Functional Partners:
EFL27582.1
Putative 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Truncated CDS; unextendable partial coding region.
  
  
  0.964
EFL22434.1
2-dehydro-3-deoxygluconokinase.
 
 
 0.955
EFL23126.1
2-keto-3-deoxygluconate kinase.
 
 
 0.926
EFL23572.1
2-keto-3-deoxygluconate kinase.
 
 
 0.924
EFL26605.1
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Unextendable partial coding region.
  
  
 
0.885
EFL23292.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
     
 0.876
EFL28209.1
Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.876
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.873
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.872
EFL27004.1
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.872
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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