Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL22445.1Conserved hypothetical protein. (345 aa)    
Predicted Functional Partners:
EFL22444.1
Conserved hypothetical protein.
 
   
 0.960
EFL23393.1
Putative ATP-dependent DNA helicase PcrA.
  
 0.889
EFL22753.1
RecQ family ATP-dependent DNA helicase; Truncated CDS.
  
 0.877
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.726
EFL20951.1
ATP-dependent DNA helicase RecQ.
  
 0.711
EFL25306.1
ATP-dependent DNA helicase PcrA.
     
  0.707
EFL21138.1
Putative nuclease sbcCD subunit C.
  
 
 0.665
EFL23676.1
Putative transcriptional regulator.
  
 
 0.663
EFL24972.1
Conserved hypothetical protein.
   
 
 0.661
recD2
RecD/TraA family helicase; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 
 0.654
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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