Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL22456.1Malate synthase A; Belongs to the malate synthase family. (539 aa)    
Predicted Functional Partners:
EFL23140.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.987
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 0.956
EFL25995.1
Citrate (Si)-synthase; Belongs to the citrate synthase family.
   
 0.955
EFL28325.1
Carboxyvinyl-carboxyphosphonate phosphorylmutase (Carboxyphosphonoenolpyruvate phosphonomutase) (CPEP phosphonomutase).
   
 0.953
EFL28489.1
Conserved hypothetical protein.
   
 0.953
EFL25238.1
Citrate (Si)-synthase; Belongs to the citrate synthase family.
   
 0.950
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.933
EFL23292.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
   
 
 0.922
EFL23529.1
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.922
EFL23270.1
Putative phosphorylmutase.
   
 0.916
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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