Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL22478.1Conserved hypothetical protein. (260 aa)    
Predicted Functional Partners:
EFL23898.1
Putative tetratricopeptide repeat protein.
  
 0.855
EFL22809.1
Sensor histidine kinase/response regulator.
   
 0.825
EFL27138.1
Sensor histidine kinase/response regulator.
   
 0.760
EFL22477.1
Putative regulatory protein.
       0.740
htpG
Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.
   
 0.689
EFL22475.1
2Fe-2S iron-sulfur cluster binding domain protein; Truncated CDS.
       0.679
EFL22476.1
Molybdopterin dehydrogenase, FAD-binding protein.
       0.679
EFL23393.1
Putative ATP-dependent DNA helicase PcrA.
   
  0.670
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.660
EFL24232.1
Acetoin utilization protein AcuC.
    
 0.651
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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