Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL22551.1LigA protein. (509 aa)    
Predicted Functional Partners:
EFL22552.1
Conserved hypothetical protein.
       0.785
EFL22553.1
Basic proline-rich protein.
       0.773
EFL21166.1
Putative efflux protein.
  
     0.763
EFL22550.1
Putative adenylate cyclase.
       0.627
EFL21553.1
ArsR family transcriptional regulator.
       0.572
EFL22554.1
GntR family transcriptional regulator.
       0.561
EFL24309.1
Conserved hypothetical protein.
   
    0.535
EFL27376.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.497
EFL22555.1
ABC transporter, ATP-binding protein.
       0.482
EFL22548.1
Putative sigma factor SigB regulation protein rsbU.
       0.433
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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