Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL22561.1LigA protein. (1098 aa)    
Predicted Functional Partners:
guaA
GMP synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
    
 0.790
EFL28082.1
Putative aminotransferase B.
    
   0.647
EFL28533.1
Putative aminotransferase.
    
   0.647
EFL22560.1
Hypothetical protein.
       0.569
EFL22703.1
Nucleic acid binding, OB-fold, tRNA/helicase-type.
     
 0.543
EFL22950.1
ATP-dependent DNA helicase RecG.
     
 0.543
EFL26109.1
Conserved hypothetical protein.
    
  0.520
EFL27529.1
LigA protein.
 
     0.424
EFL22809.1
Sensor histidine kinase/response regulator.
  
  
 0.422
EFL27825.1
Putative stage II sporulation protein E (SpoIIE).
  
    0.403
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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