STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL22678.1AraC family transcriptional regulator. (290 aa)    
Predicted Functional Partners:
EFL22272.1
Putative 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme.
  
     0.759
EFL28700.1
DsbA family thiol:disulfide interchange protein.
  
     0.759
EFL28197.1
ThiJ/PfpI.
 
     0.748
EFL22677.1
Drug transporter.
       0.556
EFL26227.1
AraC family transcriptional regulator.
  
   0.490
sigA
RNA polymerase sigma (70) factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.469
EFL24259.1
Xre family toxin-antitoxin system, antitoxin component.
  
   0.461
EFL22676.1
Putative transcriptional regulator with cyclic nucleotide-binding domain (CrP/Fnr-family).
  
    0.439
EFL23769.1
RNA polymerase principal sigma factor HrdD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.438
EFL26308.1
RNA polymerase sigma (70) factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.438
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.