Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL22727.1Type I phosphodiesterase/nucleotide pyrophosphatase superfamily protein. (390 aa)    
Predicted Functional Partners:
EFL22726.1
Thymidine kinase.
    
  0.855
EFL21385.1
Mannose-1-phosphate guanyltransferase.
  
 
 0.628
EFL21401.1
Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.
    
  0.584
EFL22865.1
Glycosyl hydrolase, family 31; Belongs to the glycosyl hydrolase 31 family.
    
  0.584
EFL25662.1
Alpha-xylosidase; Belongs to the glycosyl hydrolase 31 family.
    
  0.584
EFL26729.1
Putative alpha-N-acetylglucosaminidase; Unextendable partial coding region.
    
  0.584
EFL22730.1
HPr family phosphocarrier.
       0.572
EFL26537.1
Hypothetical protein.
       0.572
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
  0.542
EFL24562.1
Putative membrane protein.
    
  0.514
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.