Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL22738.1Putative signal transduction histidine kinase. (759 aa)    
Predicted Functional Partners:
EFL22809.1
Sensor histidine kinase/response regulator.
    
 0.909
EFL23102.1
Putative two-component response regulator.
  
 0.851
EFL26714.1
Two-component system response regulator.
  
 0.839
EFL27138.1
Sensor histidine kinase/response regulator.
    
 0.808
EFL22737.1
Conserved hypothetical protein.
     
 0.582
EFL26713.1
ATP binding protein.
 
    0.547
EFL24427.1
Transcriptional regulatory protein afsQ1.
     
 0.537
EFL20670.1
Sensor histidine kinase/response regulator.
    
 0.509
EFL21461.1
ATP binding protein.
 
    0.498
EFL26270.1
Conserved hypothetical protein.
     
 0.476
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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