STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL22739.1Sodium/solute symporter family protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (526 aa)    
Predicted Functional Partners:
EFL22740.1
Putative membrane protein.
 
  
 0.979
EFL27158.1
Putative integral membrane protein (DUF485).
 
  
 0.937
EFL28239.1
Putative integral membrane protein (DUF485).
 
  
 0.928
EFL22741.1
Two-component system, regulatory protein.
       0.563
EFL22742.1
Sensor kinase, two-component system.
       0.558
EFL22743.1
Putative integral membrane protein.
  
    0.537
acsA
acetate-CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.443
EFL21189.1
AMP-binding protein.
  
  
 0.408
EFL22469.1
Putative acetyl-CoA synthetase.
  
  
 0.408
EFL28745.1
acyl-CoA ligase; Truncated CDS.
  
  
 0.408
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.