Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL22741.1Two-component system, regulatory protein. (229 aa)    
Predicted Functional Partners:
EFL22742.1
Sensor kinase, two-component system.
 
  0.973
EFL22809.1
Sensor histidine kinase/response regulator.
  
 0.932
EFL27138.1
Sensor histidine kinase/response regulator.
   
 0.871
EFL22743.1
Putative integral membrane protein.
       0.855
EFL21514.1
Putative signal transduction histidine kinase.
  
  0.798
EFL25025.1
Histidine protein kinase sensor protein (putative).
  
   0.785
EFL22740.1
Putative membrane protein.
       0.779
EFL27190.1
Putative two-component system sensor kinase; Truncated CDS.
 
  0.777
EFL20888.1
Putative signal transduction histidine kinase.
  
  0.774
EFL25940.1
Sensor kinase, two-component system.
  
  0.770
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.