STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (233 aa)    
Predicted Functional Partners:
EFL24674.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.949
EFL23676.1
Putative transcriptional regulator.
  
 
 0.940
EFL22755.1
Conserved hypothetical protein.
   
 
 0.870
EFL26603.1
Ribonuclease HI.
  
 
 0.863
rnhA
Ribonuclease HI (RNase HI); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.821
EFL23393.1
Putative ATP-dependent DNA helicase PcrA.
  
 
 0.789
EFL27601.1
Polyketide synthase; Truncated CDS.
  
 
 0.783
EFL21634.1
Non-ribosomal peptide synthetase/polyketide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.781
EFL22757.1
Putative hydrolase.
       0.770
EFL21630.1
Non-ribosomal peptide synthetase.
  
 
 0.756
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.