STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL22798.1Endonuclease VIII. (273 aa)    
Predicted Functional Partners:
EFL22797.1
Putative ATP dependent DNA helicase.
 
  
 0.968
EFL22796.1
Putative ATP dependent DNA helicase.
 
  
 0.943
EFL22795.1
Putative ATP dependent DNA helicase.
 
  
 0.925
EFL26119.1
DNA-formamidopyrimidine glycosylase; Belongs to the FPG family.
  
  
 
0.917
EFL26955.1
DNA polymerase I.
 
  
 0.908
EFL26957.1
DNA polymerase I.
  
  
 0.893
EFL22799.1
Estradiol 17-beta-dehydrogenase 8 (Testosterone 17-beta-dehydrogenase 8) (17-beta-HSD 8) (17-beta-hydroxysteroiddehydrogenase 8).
       0.846
EFL20690.1
Putative formamidopyrimidine-DNA glycosylase; Unextendable partial coding region.
  
   
 0.837
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.731
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
  
 0.716
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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