Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL22798.1Endonuclease VIII. (273 aa)    
Predicted Functional Partners:
EFL22797.1
Putative ATP dependent DNA helicase.
 
  
 0.958
EFL22796.1
Putative ATP dependent DNA helicase.
 
  
 0.924
EFL22795.1
Putative ATP dependent DNA helicase.
 
  
 0.900
EFL26119.1
DNA-formamidopyrimidine glycosylase; Belongs to the FPG family.
  
  
 
0.892
EFL22799.1
Estradiol 17-beta-dehydrogenase 8 (Testosterone 17-beta-dehydrogenase 8) (17-beta-HSD 8) (17-beta-hydroxysteroiddehydrogenase 8).
       0.831
EFL20690.1
Putative formamidopyrimidine-DNA glycosylase; Unextendable partial coding region.
  
   
 0.810
EFL26955.1
DNA polymerase I.
 
  
 0.659
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.647
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
 
 0.641
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.606
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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