Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL22809.1Sensor histidine kinase/response regulator. (1823 aa)    
Predicted Functional Partners:
EFL20519.1
Putative membrane protein.
  
 0.999
EFL20622.1
Putative integral membrane sensor protein.
  
 0.999
EFL20670.1
Sensor histidine kinase/response regulator.
 
0.999
EFL21051.1
Putative serine/threonine kinase anti-sigma factor.
  
 0.999
EFL21288.1
Putative sensory box histidine kinase.
  
 0.999
EFL21328.1
Putative PAS fold protein.
 
 0.999
EFL21338.1
Putative membrane protein.
  
 0.999
EFL21745.1
Sensory box/GGDEF family protein.
  
 0.999
EFL22288.1
Putative membrane protein; Truncated CDS; unextendable partial coding region.
  
 0.999
EFL22564.1
Putative regulatory protein.
  
 0.999
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (12%) [HD]