Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
EFL22829.1Serine/threonine protein kinase AfsK. (722 aa)    
Predicted Functional Partners:
EFL22830.1
Serine/threonine protein kinase AfsK.
 
    
0.916
EFL22809.1
Sensor histidine kinase/response regulator.
   
 0.868
EFL28982.1
Protein phosphatase.
 
 
 0.837
EFL25274.1
Histidine kinase.
  
     0.774
EFL25504.1
Conserved hypothetical protein.
   
 
 0.736
EFL21383.1
Forkhead-associated.
 
 
 
 0.718
EFL22831.1
Putative LigA.
       0.701
EFL22828.1
Putative serine/threonine protein kinase.
 
    
0.700
EFL27138.1
Sensor histidine kinase/response regulator.
   
 0.690
EFL27396.1
Putative FK-506 binding protein, peptidyl-prolyl cis-trans isomerase.
   
 
 0.680
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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