Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL22897.1ABC transporter, periplasmic substrate-binding protein. (357 aa)    
Predicted Functional Partners:
EFL22896.1
ABC transporter integral membrane protein.
 
 
 0.997
fbpC
Fe(3+) ions import ATP-binding protein FbpC; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
 
  
 0.951
EFL21472.1
Putative ABC transporter permease protein.
  
 
 0.862
rlmN
Cfr family radical SAM enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
     0.783
EFL22899.1
Putative phosphatidate cytidylyltransferase; Belongs to the CDS family.
       0.707
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
       0.707
EFL25135.1
Sugar ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily.
    
  0.676
EFL28085.1
Sn-glycerol-3-phosphate import ATP-binding protein UgpC; Belongs to the ABC transporter superfamily.
    
  0.676
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.669
tsf
Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
       0.642
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (8%) [HD]