Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL22997.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)    
Predicted Functional Partners:
serC
Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
 
 0.978
EFL27187.1
Phosphoserine phosphatase.
  
 0.853
EFL22999.1
Acetolactate synthase, small subunit.
 
 
 0.840
EFL21377.1
Glycine dehydrogenase; Truncated CDS; Belongs to the GcvP family.
  
  
 0.817
EFL25531.1
Cystathionine beta-synthase.
  
 0.817
EFL28836.1
Hypothetical protein.
  
 
 0.812
EFL20389.1
D-isomer specific 2-hydroxyacid dehydrogenase.
 
 
0.791
EFL24122.1
Ferredoxin oxidoreductase, alpha subunit.
  
 
 0.786
EFL26926.1
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.785
EFL20406.1
FAD dependent oxidoreductase/aminomethyl transferase; Belongs to the GcvT family.
  
 0.763
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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