Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL23003.1Putative oxidoreductase. (320 aa)    
Predicted Functional Partners:
EFL21027.1
Putative sugar-phosphate dehydrogenase.
  
     0.742
EFL23005.1
Conserved hypothetical protein.
       0.719
EFL23001.1
Pas:ggdef.
       0.695
EFL23002.1
Putative dehydrogenase.
  
    0.681
EFL23000.1
Acetolactate synthase, large subunit, biosynthetic type.
  
    0.654
EFL23004.1
Putative glucose dehydrogenase.
       0.573
EFL27875.1
Aldo/keto reductase family oxidoreductase.
 
 0.514
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.513
EFL24232.1
Acetoin utilization protein AcuC.
   
   0.489
EFL23600.1
Aldo/keto reductase family oxidoreductase.
 
0.442
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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