Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL23020.1Short-chain dehydrogenase/reductase family oxidoreductase. (229 aa)    
Predicted Functional Partners:
EFL23019.1
Methionine synthase, vitamin-B12 independent.
       0.826
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
       0.814
EFL27601.1
Polyketide synthase; Truncated CDS.
  
 0.772
EFL21630.1
Non-ribosomal peptide synthetase.
  
 0.767
EFL21634.1
Non-ribosomal peptide synthetase/polyketide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.738
EFL23017.1
Diguanylate cyclase/phosphodiesterase (GGDEF EAL domains).
       0.706
EFL23021.1
Putative TetR-family transcriptional regulator.
       0.697
EFL20777.1
Polyketide synthase.
   
 0.660
EFL28210.1
Erythronolide synthase, modules 5 and 6 (ORF 3) (6-deoxyerythronolide B synthase III) (DEBS 3).
   
 0.660
EFL26930.1
Glutamate synthase large subunit.
    
  0.651
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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