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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL23328.1Glyoxylase. (140 aa)    
Predicted Functional Partners:
fabH
3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
   
   0.875
EFL22347.1
methylmalonyl-CoA mutase.
    
 0.762
icmF
B12 binding domain/ArgK/methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.700
EFL24122.1
Ferredoxin oxidoreductase, alpha subunit.
   
 
 0.693
EFL20777.1
Polyketide synthase.
  
 0.660
EFL28210.1
Erythronolide synthase, modules 5 and 6 (ORF 3) (6-deoxyerythronolide B synthase III) (DEBS 3).
  
 0.660
EFL20710.1
methylmalonyl-CoA mutase, alpha subunit.
    
 0.642
EFL20712.1
methylmalonyl-CoA mutase, beta subunit.
    
 0.642
EFL29029.1
Benzoate dioxygenase, ferredoxin reductase component.
  
 
 0.633
EFL26930.1
Glutamate synthase large subunit.
     
 0.579
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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