STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL23528.1Conserved hypothetical protein. (230 aa)    
Predicted Functional Partners:
EFL26775.1
Transcription regulator.
 
  
 0.890
EFL25278.1
Putative two-component system sensor kinase.
 
    0.847
EFL23529.1
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
       0.799
whiB-3
Putative WhiB-family transcriptional regulator putative role in cell cycle control; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
       0.774
EFL26776.1
Conserved hypothetical protein.
  
     0.728
EFL28321.1
Putative membrane protein.
  
     0.618
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.605
EFL23535.1
Conserved hypothetical protein.
       0.605
EFL24950.1
Putative integral membrane protein.
  
     0.598
EFL23305.1
Conserved hypothetical protein.
  
  
 0.559
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.