Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL23544.1Probable hydrogen peroxide-inducible genes activator; Belongs to the LysR transcriptional regulatory family. (318 aa)    
Predicted Functional Partners:
ahpD
Alkyl hydroperoxide reductase D; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
 
   
 0.918
EFL23545.1
Alkyl hydroperoxide reductase C.
 
   
 0.905
EFL24549.1
LysR family transcriptional regulator.
  
     0.755
EFL22146.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.744
EFL27412.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.705
EFL26916.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.612
EFL27475.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.525
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.488
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.451
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.442
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (14%) [HD]