Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL23594.1Hemolysin III family channel protein. (232 aa)    
Predicted Functional Partners:
EFL23595.1
TetR family transcriptional regulator.
       0.827
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
       0.748
EFL24562.1
Putative membrane protein.
    
 0.606
EFL20668.1
Conserved hypothetical protein.
       0.572
EFL28740.1
Type I polyketide synthase AVES 2; Unextendable partial coding region.
   
 
 0.526
EFL28731.1
Putative phosphopantetheine attachment site.
   
 
 0.456
EFL23420.1
ATP-dependent RNA helicase DeaD; Unextendable partial coding region; Belongs to the DEAD box helicase family.
 
 
  0.437
EFL20786.1
Polyketide synthase type I.
   
 
 0.433
EFL28164.1
Polyketide synthase type I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
   
 
 0.433
EFL28727.1
Type I polyketide synthase AVES 1.
   
 
 0.433
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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