Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL23723.1Integral membrane protein. (294 aa)    
Predicted Functional Partners:
EFL23722.1
YbaK/prolyl-tRNA synthetase associated region; Truncated CDS; unextendable partial coding region.
       0.882
EFL20931.1
Conserved hypothetical protein.
       0.572
EFL23721.1
DSBH domain-containing protein.
       0.565
EFL26445.1
3-hydroxyisobutyrate dehydrogenase.
       0.503
EFL23736.1
Putative TetR-family transcriptional regulator.
       0.498
EFL23717.1
Putative dolichyl-phosphate-mannose-protein mannosyltransferase family protein.
  
    0.485
EFL25149.1
Conserved hypothetical protein.
  
     0.449
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
   0.445
EFL21670.1
Conserved hypothetical protein.
  
     0.425
EFL21876.1
HNH endonuclease.
  
     0.422
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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