STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL23762.1acetate-CoA ligase. (168 aa)    
Predicted Functional Partners:
EFL22469.1
Putative acetyl-CoA synthetase.
 
  
  0.943
EFL23761.1
Conserved hypothetical protein.
       0.882
EFL22644.1
Benzoate-coenzyme A ligase.
 
     0.880
EFL28210.1
Erythronolide synthase, modules 5 and 6 (ORF 3) (6-deoxyerythronolide B synthase III) (DEBS 3).
 
 0.820
EFL24122.1
Ferredoxin oxidoreductase, alpha subunit.
  
 
 0.755
EFL20777.1
Polyketide synthase.
  
 0.738
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.732
EFL20786.1
Polyketide synthase type I.
  
 0.730
EFL28164.1
Polyketide synthase type I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.730
EFL28727.1
Type I polyketide synthase AVES 1.
  
 0.730
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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