STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL23814.1Aminotransferase, class IV. (258 aa)    
Predicted Functional Partners:
EFL21630.1
Non-ribosomal peptide synthetase.
  
 0.835
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.825
EFL27094.1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.825
EFL28404.1
Putative dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.825
EFL27601.1
Polyketide synthase; Truncated CDS.
  
 0.807
EFL22983.1
2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 0.801
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.801
EFL29060.1
Homocitrate synthase.
  
 0.801
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.801
EFL21634.1
Non-ribosomal peptide synthetase/polyketide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.794
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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