Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL23973.1Lipopolysaccharide biosynthesis protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (422 aa)    
Predicted Functional Partners:
EFL27778.1
Putative glucosyltransferase.
  
 
 0.948
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 
 0.892
EFL22811.1
Conserved hypothetical protein.
 
  
 0.874
EFL20718.1
NAD-dependent epimerase/dehydratase.
 
 
 0.871
EFL20791.1
3-amino-5-hydroxybenzoic acid synthase; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.857
EFL23212.1
Hexapeptide transferase.
 
 
 0.856
EFL23216.1
Daunorubicin biosynthesis sensory transduction protein DnrJ; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.852
EFL23214.1
dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
 
 0.844
EFL23215.1
Glucose-1-phosphate thymidylyltransferase.
  
 
 0.807
EFL23199.1
Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase.
  
 
 0.801
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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