Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL24288.1Signal transduction histidine-protein kinase/phosphatase MprB. (472 aa)    
Predicted Functional Partners:
EFL24289.1
DNA-binding response regulator.
 
 0.989
EFL22809.1
Sensor histidine kinase/response regulator.
  
 0.980
EFL24287.1
DNA-binding response regulator.
 
 0.980
EFL20858.1
DNA-binding response regulator TcrA.
 
 0.975
EFL22112.1
DNA-binding response regulator.
  
 0.974
EFL27138.1
Sensor histidine kinase/response regulator.
   
 0.937
EFL20857.1
Sensor histidine kinase.
  
 
 
0.889
EFL22111.1
Periplasmic sensor signal transduction histidine kinase.
  
 
0.882
EFL24292.1
Transcriptional regulatory protein GlnR.
 
 0.876
EFL22589.1
DNA-binding response regulator ResD.
  
 0.852
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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