Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL24305.1Fur family transcriptional regulator; Belongs to the Fur family. (153 aa)    
Predicted Functional Partners:
EFL24306.1
Folate-binding protein YgfZ; Belongs to the GcvT family.
       0.882
EFL24304.1
Conserved hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands.
  
    0.793
EFL26930.1
Glutamate synthase large subunit.
    
 0.792
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.735
EFL24303.1
Conserved hypothetical protein.
       0.708
EFL20576.1
Putative hydrogen peroxide sensitive repressor; Belongs to the Fur family.
  
     0.688
EFL23545.1
Alkyl hydroperoxide reductase C.
  
  
 0.673
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.642
EFL27016.1
Putative DNA-binding transcriptional regulator.
  
    0.642
EFL21157.1
Putative CoA binding domain protein.
  
    0.595
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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